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Home/Applications/Life science/Process feeding and sampling
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Tubing and fittings in process feeding and sampling

Application guide

This page explains the positions, supporting components and configuration requirements of tubing and fittings connecting process vessels and fluid branches, with links to feeding and sampling operations and validation tasks.

Application guides

Process feeding and sampling application guide

Fluidic Overview for Process Feeding and Sampling
Syringe pumps in process feeding and sampling
Online sampling
Valveless metering pumps in process feeding and sampling
Feeding
Fluidic Valves for Process Feeding and Sampling
Bubble and pressure sensing in process feeding and sampling
Tubing and fittings in process feeding and sampling

ON THIS PAGE

What do these products do in this instrument?Design tubing and fittings as a complete wetted pathCalculate connection volume and post-maintenance recoveryTranslate actual branch conditions into configuration requirementsCompare product configurations by the roles on this pageConfirm product roles in actual operationDoes a fitting that tightens prove the tubing assembly is suitable?ReferencesRelated guides

01What do these products do in this instrument?

Tubing and Fittings: Connecting Process Vessels and Fluid Branches

Form feed, sample and waste paths, choosing wetted materials for the actual formulation and operating duration. After maintenance, check assembly, sealing, priming and volume records before restarting the task.

Tubing and fittings together form sealed connections and the actual transfer path. Check formulation, inner/outer diameters, length, tube-end positioning and port geometry, including added volume in residue and arrival delay.

02Design tubing and fittings as a complete wetted path

Tubing, fittings and ports jointly determine sealing, transfer volume and medium-contact coverage. Materials and dimensions must suit formulation, operating conditions and installation. Include tubing length and interface volume in priming, shared residue and arrival delay. After connection changes, recheck delivery and cleaning through the actual path.

03Calculate connection volume and post-maintenance recovery

Shared volume affects liquid arrival and flushing; interface gaps may retain the previous composition. Record length, actual bore and tube insertion position. After disassembly, reprime and check seals, then compare first-cycle delivery, blanks or recovered product to confirm path recovery.

04Translate actual branch conditions into configuration requirements

Tubing and Fitting Configuration for Process Feeding and Sampling
ConditionTo confirm
Materials and assemblyProvide formulation, tubing inner/outer diameters, length, fitting structure and port fit.
Volume and loadCalculate shared and replacement-component added volumes; measure actual flow and response.
Maintenance recoveryRecord disassembly locations and added volume; recheck priming, sealing and first-cycle received results.

05Compare product configurations by the roles on this page

Configuration options for the product roles on this page
ProductConfiguration optionConditions to verify
Tubing materials and dimensionsConnection paths and shared volumeBore, length, load and actual formulation jointly determine materials and dimensions
Rigid-tubing fittingsTube-end positioning and sealed connectionsCheck tube outer diameter, threads, seal structure and port-bottom geometry
  • Tubing materials and dimensions
  • Rigid-tubing fittings

06Confirm product roles in actual operation

Connect the culture process, actual feeding and sample analysis, retaining records across the entire run.

07Does a fitting that tightens prove the tubing assembly is suitable?

Also confirm port geometry, tube-end positioning and seal fit. Check leakage, hold-up and performance after repeated maintenance under actual conditions; thread engagement alone is insufficient.

Periodic dispensing, continuous feeding and aseptic sampling have different requirements. A single metering test cannot establish all three.

References

View references (2)
  1. [1]FOREACH tubing materials and dimensions: configurations and specifications
  2. [2]FOREACH rigid-tubing fittings: configurations and specifications

Related guides

  • Back to the process feeding and sampling fluidics overview

Related Products

Tubing materials and dimensions; representative configuration. Select capacity, materials and interfaces for the application.

Tubing materials and dimensions

Rigid-tubing fittings; representative configuration. Select capacity, materials and interfaces for the application.

Rigid-tubing fittings

Related Technical Articles

What is flow resistance calculation for? Using the Foreach calculator in fluid-path design and selection

The free flow rate of the pump meets the requirements. After installing the pipelines, valves and joints, the liquid supply at the end is insufficient. Flow resistance calculations can break the problem down into comparable data: what pressure differential is required at the target flow rate, where does the pressure loss mainly occur, and what happens if the pipe diameter, pipe length, component Cv or medium viscosity is changed. This article combines the actual function of the Foreach flow resistance calculator with a recalculable fluid circuit case to explain how to use the calculation results for design, selection, troubleshooting and prototype verification.

2026-09-11View Details

Why Does Actual Flow Change So Much When the Tubing Size Changes on the Same Miniature Diaphragm Pump?

Even when the pump is unchanged, installed flow can change because of tubing inner diameter, length, bends, and the minimum bore of fittings. When flow falls after a tubing change, the effective response is neither to blame the pump first nor to enlarge every tube indiscriminately. Measure inlet pressure, outlet pressure, and accumulated flow together to determine where the added restriction actually occurs.

2026-08-24View Details

Valveless Metering Pump Selection Guide: FOREACH Models and Applications

To select a valveless metering pump, first define the volume per dose and the time available for dispensing. Then check displacement per revolution, drive speed, wetted materials, backpressure and connections, and verify delivery in the actual fluid path. Neither flow rate alone nor the label ‘metering pump’ is enough to select a model.

2026-09-16View Details

Discuss fluidic configurations for life science processes

Provide a fluid diagram, the actual liquids and pressures in each state. Bore size, length, load and actual formulation jointly determine material and dimensional choices. Check tubing OD, threads, sealing structure and port-bottom geometry. Compare suitable configurations against the validation objectives described here.

Contact an engineer