What do these products do in this instrument?
Tubing and Fittings: Long-Term Wetted Paths and Sealed Module Connections
Connect culture vessels, feed, sampling and waste modules. Confirm materials and seals for temperature, run duration and maintenance procedures. After disassembly, recheck contamination boundaries and actual routing before resuming automatic operation.
Tubing and fittings together form sealed connections and the actual transfer path. Check formulation, inner/outer diameters, length, tube-end positioning and port geometry, including added volume in residue and arrival delay.
Design tubing and fittings as a complete wetted path
Tubing, fittings and ports jointly determine sealing, transfer volume and medium-contact coverage. Materials and dimensions must suit formulation, operating conditions and installation. Include tubing length and interface volume in priming, shared residue and arrival delay. After connection changes, recheck delivery and cleaning through the actual path.
Calculate connection volume and post-maintenance recovery
Shared volume affects liquid arrival and flushing; interface gaps may retain the previous composition. Record length, actual bore and tube insertion position. After disassembly, reprime and check seals, then compare first-cycle delivery, blanks or recovered product to confirm path recovery.
Translate actual branch conditions into configuration requirements
| Condition | To confirm |
|---|---|
| Materials and assembly | Provide formulation, tubing inner/outer diameters, length, fitting structure and port fit. |
| Volume and load | Calculate shared and replacement-component added volumes; measure actual flow and response. |
| Maintenance recovery | Record disassembly locations and added volume; recheck priming, sealing and first-cycle received results. |
| Operation | Specific operating conditions |
|---|---|
| Module connections | Tubing ID/OD, length, interface geometry, pressure, materials and maintenance method |
Module connections
Confirm wetted materials, seals and replacement methods between culture vessels, reagents, waste and sensors. Validate connections for cleaning or sterilization and extended temperature exposure. Recheck contamination boundaries after maintenance.
Evaluate materials, seals and connection methods against temperature and cleaning or sterilization procedures. Recheck contamination boundaries after maintenance before releasing automatic operation.
Check leaks, tube disconnection and material changes at actual pressure and temperature; evaluate residue, recovery and the first post-maintenance cycle through the complete path
Misconnections, gaps, tube deformation or leaks may alter volume and pressure. Isolate the affected segment and reconfirm assembly; matching threads do not establish interchangeability.
Compare product configurations by the roles on this page
| Product | Configuration option | Conditions to verify |
|---|---|---|
| Tubing materials and dimensions | Connection paths and shared volume | Bore, length, load and actual formulation jointly determine materials and dimensions |
| Rigid-tubing fittings | Tube-end positioning and sealed connections | Check tube outer diameter, threads, seal structure and port-bottom geometry |
Confirm product roles in actual operation
| Operation | Measurements and observations | Priority checks |
|---|---|---|
| Module connections | Check leaks, tube disconnection and material changes at actual pressure and temperature; evaluate residue, recovery and the first post-maintenance cycle through the complete path | Misconnections, gaps, tube deformation or leaks may alter volume and pressure |
Include extended operation, power loss, depleted feed, blockage and post-maintenance restart. Check cumulative delivery and contamination boundaries.
Does a fitting that tightens prove the tubing assembly is suitable?
Also confirm port geometry, tube-end positioning and seal fit. Check leakage, hold-up and performance after repeated maintenance under actual conditions; thread engagement alone is insufficient.
Evaluate fluidic feedback and biological process results separately. A component combination alone does not establish sterility or continuous-culture capability.