What do these products do in this instrument?
Multiport rotary valves: connecting multiple process tasks
Route feeding, sampling and maintenance in source-selection configurations, coordinated with interlocks and culture-vessel identity. Define operating and fault states, checking unintended connections and closed-state isolation.
MRV3 selects sources or destinations and requires a port-state diagram and shared-volume budget. Port count indicates routing options; confirm pressure in each state and independent simultaneous supply requirements separately.
Pinch-valve arrangements: flexible-path isolation and module maintenance
Open or close branches at the actual tubing-control locations, coordinated with module replacement and process restart. Confirm tubing, fittings, closure sealing and cleaning or sterilization steps together.
Discuss tubing pinch-off for the specific project. Tubing and fittings define the liquid-contact path. Validate tubing material, wall thickness, pinch seal and replacement procedure together, and assess cleaning or sterilization across the complete path.
Define connections using the instrument's port-state diagram
This page covers multiport rotary valves and tubing pinch-off solutions. Identify every port, current source, receiving destination and branch requiring isolation. Check connectivity during aspiration, delivery, washing, maintenance and power loss. Valve selection actions must correspond to permitted drive conditions.
Include renewal of shared segments after switching in the sequence
After source switching, shared tubing may retain the previous composition. Record volume and arrival delay from the new source to the receiver, and measure residue and recovery for the actual worst-case switching combination. Confirm port positioning and arrival of new liquid separately.
Translate actual branch conditions into configuration requirements
| Condition | To confirm |
|---|---|
| Connections and pressure | Provide port diagrams and pressure conditions for all operating, cleaning and shutdown states. |
| Shared volume | Identify residue locations after source changes, flushing volumes and discharge destinations. |
| Control and isolation | Check valve-position feedback, pump actions, shutoff leakage and permitted power-off states. |
| Operation | Specific operating conditions |
|---|---|
| Paths and interlocks | Task state, sample or vessel identity, concurrent resources, interlocks and restart |
Compare product configurations by the roles on this page
| Product | Configuration option | Conditions to verify |
|---|---|---|
| MRV3 multiport rotary valve | Multiple-source selection | Compare 10-, 16- and 24-port options and port diagrams; verify high-pressure suitability separately |
Explore specific operating and validation tasks
Paths and interlocks
Concurrent tasks must prevent wash liquid, waste or other formulations entering culture paths. Include fault states and maintenance bypasses on the same drawings.
Confirm product roles in actual operation
| Operation | Measurements and observations | Priority checks |
|---|---|---|
| Paths and interlocks | Test concurrent operation, limiting states and complete fault recovery; verify that identities, cumulative quantities and records match actual actions | Resource conflicts, communication loss or mismatched identities can cause delivery to the wrong destination or repeated dosing. |
Include extended operation, power loss, depleted feed, blockage and post-maintenance restart. Check cumulative delivery and contamination boundaries.
Do more valve ports mean more channels can supply liquid simultaneously?
Check port connection structure and drive configuration. The number of selectable sources, independent paths and simultaneous-operation capability are different conditions, determined by actual connections in each state.
Evaluate fluidic feedback and biological process results separately. A component combination alone does not establish sterility or continuous-culture capability.