What do these products do in this instrument?
Bubble and pressure sensing: monitor interrupted supply and abnormal load
Monitor bubbles or pressure changes in the actual supply branch. The controller links anomaly timing to cumulative replenishment records. Evaluate culture condition with the relevant bioprocess measurements before the controller permits continuation.
ABD provides bubble or liquid-state signals for defined tubing; PDM5 provides pressure information at a defined location. Configure module, position and action window separately; the controller associates affected samples or tasks.
Match sensing locations to specific fluidic problems
Bubble modules report bubble or liquid state in defined tube segments; pressure modules report pressure at defined positions. Before selecting mounting points, define the phase and abnormality to observe: aspiration, delivery, source depletion or branch-load changes. Associate sensor positions with affected samples, cuvettes or stations.
Connect signals, action windows and recovery conditions
The same signal may mean different things at different valve positions or operating phases. Record normal ranges and faults with actual liquids, tubing and sequences. The controller combines action timing, confirmed delivery status, volume records and sample identity to pause, review or recover; one pressure change cannot directly identify a blockage location or specific cause. Distinguish measured, estimated and unknown volumes; completion of a command does not prove actual liquid delivery.
Translate actual branch conditions into configuration requirements
| Condition | To confirm |
|---|---|
| Installation conditions | Specify tubing dimensions, liquid, sensing location and branch to observe. |
| Timing and baseline | Record valve positions, pump actions, normal changes and fault-detection windows. |
| Abnormality handling | Associate affected containers with confirmed delivery status and volume records; define conditions for review, continuation or re-execution. Distinguish measured, estimated and unknown volumes; completion of a command does not prove actual liquid delivery. |
| Operation | Specific operating conditions |
|---|---|
| State monitoring | Specific sensor configuration, location, liquid/tubing, sampling rate, threshold and time window |
State monitoring
Monitor bubbles, pressure and liquid-supply conditions in replenishment, transfer and drainage branches. Define acceptable variation and stop conditions before selecting monitoring positions and control logic. Assess cell condition independently.
Pressure and bubble signals can help identify supply anomalies. Culture condition requires relevant biological process measurements, and actual cumulative volume in the culture vessel still needs confirmation after supply resumes.
Measure fault detection, false alarms and end-to-end response separately; cover baseline changes with liquid, speed and operating conditions
Normal air segments, viscosity changes and sampling delays may be misclassified. The controller determines task validity; sensors alone do not prove dose or assay results.
Compare product configurations by the roles on this page
| Product | Configuration option | Conditions to verify |
|---|---|---|
| ABD bubble-detection module | Bubble or liquid-state identification in defined tubing | Validate detection and false alarms for tubing material, dimensions, medium and action window |
| PDM5 pressure-detection module | Pressure-state monitoring at a defined fluidic location | Confirm range and wetted configuration by model; validate normal baseline and abnormalities separately |
Confirm product roles in actual operation
| Operation | Measurements and observations | Priority checks |
|---|---|---|
| State monitoring | Measure fault detection, false alarms and end-to-end response separately; cover baseline changes with liquid, speed and operating conditions | Normal air segments, viscosity changes and sampling delays may be misclassified |
Compare viability, recovery and cell condition before and after transfer, and validate the required contamination controls.
Can dispensing be repeated immediately after bubbles or abnormal pressure are detected?
First establish whether partial delivery has occurred and which container is affected. Immediate repetition may double-dose it. Act on the actual state and recheck the first cycle after recovery.
Low shear and sterility are validation objectives for the complete flow path. Neither a diaphragm pump nor a pinch valve alone establishes them.