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Home/Applications/Analytical instruments/Analytical system integration
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Tubing and Fittings for Analytical System Integration

Application guide

This page explains tubing and fitting locations, coordination and configuration requirements for paths and sealed connections between modules in analytical system integration, with links to relevant operating and validation tasks.

Application guides

Analytical system integration application guide

Analytical system integration fluidics overview
Piston Pumps for Analytical System Integration
Syringe pumps in analytical system integration
Valveless metering pumps in analytical system integration
Diaphragm pumps in analytical system integration
Fluidic Valves for Analytical System Integration
Ports and interlocks
Bubble and pressure sensing in analytical system integration
Tubing and Fittings for Analytical System Integration

ON THIS PAGE

What do these products do in this instrument?Design tubing and fittings as a complete wetted pathCalculate connection volume and post-maintenance recoveryTranslate actual branch conditions into configuration requirementsModule connectionsCompare product configurations by the roles on this pageConfirm product roles in actual operationDoes a fitting that tightens prove the tubing assembly is suitable?ReferencesRelated guides

01What do these products do in this instrument?

Tubing and fittings: sealed paths between modules

Connect sample, standard, pump, reaction and waste modules, identifying independent and shared sections. After installation, check priming, leakage, arrival delay and method blanks. Repeat checks after repairs.

Tubing and fittings together form sealed connections and the actual transfer path. Check formulation, inner/outer diameters, length, tube-end positioning and port geometry, including added volume in residue and arrival delay.

02Design tubing and fittings as a complete wetted path

Tubing, fittings and ports jointly determine sealing, transfer volume and medium-contact coverage. Materials and dimensions must suit formulation, operating conditions and installation. Include tubing length and interface volume in priming, shared residue and arrival delay. After connection changes, recheck delivery and cleaning through the actual path.

03Calculate connection volume and post-maintenance recovery

Shared volume affects liquid arrival and flushing; interface gaps may retain the previous composition. Record length, actual bore and tube insertion position. After disassembly, reprime and check seals, then compare first-cycle delivery, blanks or recovered product to confirm path recovery.

04Translate actual branch conditions into configuration requirements

Tubing and fitting configuration for analytical system integration
ConditionTo confirm
Materials and assemblyProvide formulation, tubing inner/outer diameters, length, fitting structure and port fit.
Volume and loadCalculate shared and replacement-component added volumes; measure actual flow and response.
Maintenance recoveryRecord disassembly locations and added volume; recheck priming, sealing and first-cycle received results.
Operations supported in this instrument
OperationSpecific operating conditions
Module connectionsTubing ID/OD, length, interface geometry, pressure, materials and maintenance method

05Module connections

Account for volume, response delay and maintenance when connecting metering, reaction and detection modules. After installation, validate sealing, priming, blanks and actual signal recovery before method testing.

After assembly, validate priming, leakage, blanks and delay first. Compatible module dimensions do not establish that method results remain unaffected.

Check leaks, tube disconnection and material changes at actual pressure and temperature; evaluate residue, recovery and the first post-maintenance cycle through the complete path

Misconnections, gaps, tube deformation or leaks may alter volume and pressure. Isolate the affected segment and reconfirm assembly; matching threads do not establish interchangeability.

06Compare product configurations by the roles on this page

Configuration options for the product roles on this page
ProductConfiguration optionConditions to verify
Tubing materials and dimensionsConnection paths and shared volumeBore, length, load and actual formulation jointly determine materials and dimensions
Rigid-tubing fittingsTube-end positioning and sealed connectionsCheck tube outer diameter, threads, seal structure and port-bottom geometry
  • Tubing materials and dimensions
  • Rigid-tubing fittings

07Confirm product roles in actual operation

Operating-point validation and fault localization
OperationMeasurements and observationsPriority checks
Module connectionsCheck leaks, tube disconnection and material changes at actual pressure and temperature; evaluate residue, recovery and the first post-maintenance cycle through the complete pathMisconnections, gaps, tube deformation or leaks may alter volume and pressure

Check delivery, response, blanks and fault recovery through the complete method cycle.

08Does a fitting that tightens prove the tubing assembly is suitable?

Also confirm port geometry, tube-end positioning and seal fit. Check leakage, hold-up and performance after repeated maintenance under actual conditions; thread engagement alone is insufficient.

Configure metering, continuous supply, liquid washing and air-containing waste removal separately. See Laboratory Automation for platform scheduling.

References

View references (2)
  1. [1]FOREACH tubing materials and dimensions: configurations and specifications
  2. [2]FOREACH rigid-tubing fittings: configurations and specifications

Related guides

  • Back to analytical system integration fluidics

Related Products

Tubing materials and dimensions; representative configuration. Select capacity, materials and interfaces for the application.

Tubing materials and dimensions

Rigid-tubing fittings; representative configuration. Select capacity, materials and interfaces for the application.

Rigid-tubing fittings

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2026-09-11View Details

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Discuss fluidic configurations for analytical system integration

Provide a fluid diagram, the actual liquids and pressures in each state. Bore size, length, load and actual formulation jointly determine material and dimensional choices. Check tubing OD, threads, sealing structure and port-bottom geometry. Compare suitable configurations against the validation objectives described here.

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