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Home/Applications/Laboratory automation/Reagent dispensing
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Syringe pumps in reagent dispensing

Application guide

Explore syringe-pump placement, coordination and configuration for batch reagent aspiration and individual dispensing, with links to operating and validation tasks.

Application guides

Reagent dispensing application guide

Fluidic Overview for Reagent Dispensing
Syringe pumps in reagent dispensing
Valveless metering pumps in reagent dispensing
Repeated dispensing
Fluidic valves in reagent dispensing
Bubble and Pressure Monitoring for Reagent Dispensing
Tubing and Fittings for Reagent Dispensing

ON THIS PAGE

What do these products do in this instrument?Organize syringe metering around aspiration, holding and dispensingMap valve connections to every actionTranslate actual branch conditions into configuration requirementsCompare product configurations by the roles on this pageConfirm product roles in actual operationFor repeated dispensing from one chamber, is checking total volume enough?ReferencesRelated guides

01What do these products do in this instrument?

Syringe pumps: batch reagent aspiration and dose-by-dose dispensing

In syringe-driven dispensing, aspirate and dispense repeatedly in coordination with valve position and destination identity. Plan replenishment from usable stroke and check first, middle and last doses separately.

HLD and HMD organize aspiration/dispensing paths with rotary and solenoid valves respectively. Capacity budgets include useful volume, holding stages and replenishment points; valve states and pump actions together create each delivery.

02Organize syringe metering around aspiration, holding and dispensing

Syringe drives use controlled displacement for aspiration, holding and dispensing. With direct contact, source liquid enters the metering chamber; with system-liquid drive, sample can remain at the probe tip or a designated tube segment. Define wetted coverage before capacity, cleaning and replenishment. For repeated dispensing, track current inventory, delivered volume and next replenishment time.

03Map valve connections to every action

Check port connections, opening/closing sequence and power-off state separately for rotary- and solenoid-valve configurations. Changing source does not automatically remove old liquid from the chamber or shared tubing. Plan flushing for formulation and residue requirements, then evaluate the first dose after switching and dose-to-dose variation.

04Translate actual branch conditions into configuration requirements

Syringe-pump configuration for reagent dispensing
ConditionTo confirm
Stored volume and timingDefine volume per operation, consecutive dispensing count, holding time and permitted replenishment window.
Valve positions and destinationsProvide a source, receiver and waste port diagram with open/closed and power-off states.
Liquid changes and first doseCheck shared residue, priming destination and actual received volume after standby or source changes.

05Compare product configurations by the roles on this page

Configuration options for the product roles on this page
ProductConfiguration optionConditions to verify
HLD rotary-valve syringe pumpAspiration, holding and dispensing with a rotary valveCheck source/outlet valve positions, capacity budget and replenishment timing
HMD solenoid-valve syringe pumpMetered aspiration and dispensing with solenoid valvesCheck open/closed and power-off states, working volume and replenishment cycle
  • HLD rotary-valve syringe pump
  • HMD solenoid-valve syringe pump

06Confirm product roles in actual operation

Include first, middle and last batch doses, recovery after bottle changes, and extended operation with the actual medium.

07For repeated dispensing from one chamber, is checking total volume enough?

Measure each received dose, especially the first and last. Even when total volume is near target, individual errors may differ. Relate replenishment, valve switching and receiving actions to each result.

Repeated dosing and continuous supply are different modes. Valveless metering also requires validation with the actual medium and operating conditions.

References

View references (2)
  1. [1]FOREACH HLD rotary-valve syringe pump: configurations and specifications
  2. [2]FOREACH HMD solenoid-valve syringe pump: configurations and specifications

Related guides

  • Back to reagent dispensing fluidics

Related Products

HLD rotary-valve syringe pump; representative configuration. Select capacity, materials and interfaces for the application.

HLD rotary-valve syringe pump

HMD solenoid-valve syringe pump; representative configuration. Select capacity, materials and interfaces for the application.

HMD solenoid-valve syringe pump

Related Technical Articles

What Is a Programmable Syringe Pump? Operation, Fluid Routing and Automation

A programmable syringe pump uses a motor to control syringe plunger displacement and speed, executing aspiration, dispensing, pauses and repeated actions through commands. With a routing valve, it can connect reagent reservoirs, reaction vessels and wash paths into an automated dispensing process. Instrument development therefore needs to define volume, fluid connections and timing together.

2026-09-28View Details

What Is Pipetting? Manual and Automated Workflows Compared

Pipetting is the transfer of a specified volume of liquid from one location to another. Examples include moving 100 µL from a sample tube into a reaction vessel, or adding sample and diluent in a defined ratio.

2026-09-29View Details

Discuss a reagent dispensing fluidic configuration

Provide a fluid-path diagram, actual liquids and pressures in every state. Specify source and outlet valve positions, capacity budgets and refill timing, including open, closed and power-off states, working volumes and replenishment cycles. Compare configurations against the validation objectives in this guide.

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