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Home/Applications/Laboratory automation/Sample preparation platforms
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Multiport rotary valves in sample preparation platforms

Application guide

This page explains the multiport rotary valve's position, supporting components and configuration requirements for source, workstation and maintenance-path selection in sample preparation platforms, with links to operating and validation tasks.

Application guides

Sample preparation platform application guide

Sample preparation platform fluidics overview
Syringe pumps in sample preparation platforms
Air-displacement pipetting pumps in sample preparation platforms
Disposable-tip sample transfer
Diaphragm pumps in sample preparation platforms
Washing and product recovery
Multiport rotary valves in sample preparation platforms
Path scheduling
Bubble and pressure detection in sample preparation platforms
Tubing and fittings in sample preparation platforms

ON THIS PAGE

What do these products do in this instrument?Define connections using the instrument's port-state diagramInclude renewal of shared segments after switching in the sequenceTranslate actual branch conditions into configuration requirementsCompare product configurations by the roles on this pageExplore specific operating and validation tasksConfirm product roles in actual operationDo more valve ports mean more channels can supply liquid simultaneously?ReferencesRelated guides

01What do these products do in this instrument?

Multiport rotary valves: selecting sources, stations and maintenance paths

Establish the current connection in fixed paths with multiple sources or stations, coordinated with metering drives and task scheduling. Record the current sample, valve position and target vessel together, and define where displaced shared-path liquid goes.

MRV3 selects sources or destinations and requires a port-state diagram and shared-volume budget. Port count indicates routing options; confirm pressure in each state and independent simultaneous supply requirements separately.

02Define connections using the instrument's port-state diagram

This page covers multiport rotary valves. Mark every port, current source, receiving destination and branch requiring isolation, and check connections during aspiration, delivery, cleaning, maintenance and power loss. Valve selection must correspond to conditions permitting the drive action.

03Include renewal of shared segments after switching in the sequence

After source switching, shared tubing may retain the previous composition. Record volume and arrival delay from the new source to the receiver, and measure residue and recovery for the actual worst-case switching combination. Confirm port positioning and arrival of new liquid separately.

04Translate actual branch conditions into configuration requirements

Multiport rotary valve configuration requirements for sample preparation platforms
ConditionTo confirm
Connections and pressureProvide port diagrams and pressure conditions for all operating, cleaning and shutdown states.
Shared volumeIdentify residue locations after source changes, flushing volumes and discharge destinations.
Control and isolationCheck valve-position feedback, pump actions, shutoff leakage and permitted power-off states.
Operations supported in this instrument
OperationSpecific operating conditions
Path schedulingAll ports, valve states, pressures in each state, shared volume and flushing volume

05Compare product configurations by the roles on this page

Configuration options for the product roles on this page
ProductConfiguration optionConditions to verify
MRV3 multiport rotary valveMultiple-source selectionCompare 10-, 16- and 24-port options and port diagrams; verify high-pressure suitability separately
  • MRV3 multiport rotary valve

06Explore specific operating and validation tasks

Path scheduling

Port count alone does not establish whether one pump or valve can serve simultaneous tasks. Define occupancy, release and displacement conditions for each action to prevent conflicting resource use.

  • Path scheduling

07Confirm product roles in actual operation

Operating-point validation and fault localization
OperationMeasurements and observationsPriority checks
Path schedulingCheck unintended connections, leakage, backflow and post-switching residue in each state; measure flushing volume and arrival delay through the complete pathMisalignment, shared-segment residue or abnormal switching pressure may affect the next task

Validate working volume, timing across workstations, sample identity and the first operation after restart together.

08Do more valve ports mean more channels can supply liquid simultaneously?

Check port connection structure and drive configuration. The number of selectable sources, independent paths and simultaneous-operation capability are different conditions, determined by actual connections in each state.

Successful platform operation does not replace assessment of nucleic acid, cell or analytical method results.

References

View references (1)
  1. [1]FOREACH MRV3 multiport rotary valve: configurations and specifications

Related guides

  • Return to the sample preparation workstation overview
  • Path scheduling

Related Products

MRV3 multiport rotary valve; representative configuration. Select capacity, materials and interfaces for the application.

MRV3 multiport rotary valve

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Discuss fluidic configurations for your sample preparation workstation

Provide a fluid diagram, the actual liquids and pressures in each state. Compare 10-, 16- and 24-port configurations against the port map, and assess high-pressure suitability separately. Compare suitable configurations against the validation objectives described here.

Contact an engineer