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Home/Applications/Laboratory automation/Sample preparation platforms
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Tubing and fittings in sample preparation platforms

Application guide

This page explains tubing and fitting locations, coordination and configuration requirements for connections between stations and shared resources in sample preparation platforms, with links to relevant operating and validation tasks.

Application guides

Sample preparation platform application guide

Sample preparation platform fluidics overview
Syringe pumps in sample preparation platforms
Air-displacement pipetting pumps in sample preparation platforms
Disposable-tip sample transfer
Diaphragm pumps in sample preparation platforms
Washing and product recovery
Multiport rotary valves in sample preparation platforms
Path scheduling
Bubble and pressure detection in sample preparation platforms
Tubing and fittings in sample preparation platforms

ON THIS PAGE

What do these products do in this instrument?Design tubing and fittings as a complete wetted pathCalculate connection volume and post-maintenance recoveryTranslate actual branch conditions into configuration requirementsModule connectionsCompare product configurations by the roles on this pageRelated operations and architecture comparisonsConfirm product roles in actual operationDoes a fitting that tightens prove the tubing assembly is suitable?ReferencesRelated guides

01What do these products do in this instrument?

Tubing and fittings: connect stations and shared resources

Form the actual paths for sources, metering, washing and waste, distinguishing independent and shared sections. After replacing modules, verify identification, sealing, priming and delivery at each station.

Tubing and fittings together form sealed connections and the actual transfer path. Check formulation, inner/outer diameters, length, tube-end positioning and port geometry, including added volume in residue and arrival delay.

02Design tubing and fittings as a complete wetted path

Tubing, fittings and ports jointly determine sealing, transfer volume and medium-contact coverage. Materials and dimensions must suit formulation, operating conditions and installation. Include tubing length and interface volume in priming, shared residue and arrival delay. After connection changes, recheck delivery and cleaning through the actual path.

03Calculate connection volume and post-maintenance recovery

Shared volume affects liquid arrival and flushing; interface gaps may retain the previous composition. Record length, actual bore and tube insertion position. After disassembly, reprime and check seals, then compare first-cycle delivery, blanks or recovered product to confirm path recovery.

04Translate actual branch conditions into configuration requirements

Tubing and Fitting Configuration for Sample Preparation Workstations
ConditionTo confirm
Materials and assemblyProvide formulation, tubing inner/outer diameters, length, fitting structure and port fit.
Volume and loadCalculate shared and replacement-component added volumes; measure actual flow and response.
Maintenance recoveryRecord disassembly locations and added volume; recheck priming, sealing and first-cycle received results.
Operations supported in this instrument
OperationSpecific operating conditions
Module connectionsTubing ID/OD, length, interface geometry, pressure, materials and maintenance method

05Module connections

Record tube length, bore, wetted materials and module identity during assembly. After maintenance or replacement, verify connections, priming and delivery, using path volume to define restart procedures.

Record module identity, tubing length and wetted materials. After installation, verify sealing, priming and delivery at each workstation. Confirm successful replacement under actual operating conditions.

Check leaks, tube disconnection and material changes at actual pressure and temperature; evaluate residue, recovery and the first post-maintenance cycle through the complete path

Misconnections, gaps, tube deformation or leaks may alter volume and pressure. Isolate the affected segment and reconfirm assembly; matching threads do not establish interchangeability.

06Compare product configurations by the roles on this page

Configuration options for the product roles on this page
ProductConfiguration optionConditions to verify
Tubing materials and dimensionsConnection paths and shared volumeBore, length, load and actual formulation jointly determine materials and dimensions
Rigid-tubing fittingsTube-end positioning and sealed connectionsCheck tube outer diameter, threads, seal structure and port-bottom geometry
  • Tubing materials and dimensions
  • Rigid-tubing fittings

07Related operations and architecture comparisons

Washing and product recovery

When several stations wash simultaneously, shared supply and waste removal can become bottlenecks. Calculate peak demand first, then assess residual liquid and recovery through the complete workflow.

  • Washing and product recovery

08Confirm product roles in actual operation

Operating-point validation and fault localization
OperationMeasurements and observationsPriority checks
Module connectionsCheck leaks, tube disconnection and material changes at actual pressure and temperature; evaluate residue, recovery and the first post-maintenance cycle through the complete pathMisconnections, gaps, tube deformation or leaks may alter volume and pressure

Validate working volume, timing across workstations, sample identity and the first operation after restart together.

09Does a fitting that tightens prove the tubing assembly is suitable?

Also confirm port geometry, tube-end positioning and seal fit. Check leakage, hold-up and performance after repeated maintenance under actual conditions; thread engagement alone is insufficient.

Successful platform operation does not replace assessment of nucleic acid, cell or analytical method results.

References

View references (2)
  1. [1]FOREACH tubing materials and dimensions: configurations and specifications
  2. [2]FOREACH rigid-tubing fittings: configurations and specifications

Related guides

  • Return to the sample preparation workstation overview

Related Products

Tubing materials and dimensions; representative configuration. Select capacity, materials and interfaces for the application.

Tubing materials and dimensions

Rigid-tubing fittings; representative configuration. Select capacity, materials and interfaces for the application.

Rigid-tubing fittings

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The free flow rate of the pump meets the requirements. After installing the pipelines, valves and joints, the liquid supply at the end is insufficient. Flow resistance calculations can break the problem down into comparable data: what pressure differential is required at the target flow rate, where does the pressure loss mainly occur, and what happens if the pipe diameter, pipe length, component Cv or medium viscosity is changed. This article combines the actual function of the Foreach flow resistance calculator with a recalculable fluid circuit case to explain how to use the calculation results for design, selection, troubleshooting and prototype verification.

2026-09-11View Details

Why Does Actual Flow Change So Much When the Tubing Size Changes on the Same Miniature Diaphragm Pump?

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Discuss fluidic configurations for your sample preparation workstation

Provide a fluid diagram, the actual liquids and pressures in each state. Bore size, length, load and actual formulation jointly determine material and dimensional choices. Check tubing OD, threads, sealing structure and port-bottom geometry. Compare suitable configurations against the validation objectives described here.

Contact an engineer