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Home/Applications/Laboratory automation/Sample preparation platforms
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Sample Preparation Workstations: Path Scheduling

Application guide

This guide covers path scheduling in sample preparation platforms: component roles, action sequence, operating conditions and restart requirements. Identify the architecture before comparing configurations.

Application guides

Sample preparation platform application guide

Sample preparation platform fluidics overview
Syringe pumps in sample preparation platforms
Air-displacement pipetting pumps in sample preparation platforms
Disposable-tip sample transfer
Diaphragm pumps in sample preparation platforms
Washing and product recovery
Multiport rotary valves in sample preparation platforms
Path scheduling
Bubble and pressure detection in sample preparation platforms
Tubing and fittings in sample preparation platforms

ON THIS PAGE

Where path scheduling occurs in the instrumentProduct responsibilities in this operationOrganize the sequence by actual architectureDefine operating conditions for this taskCompare product configurations by the roles on this pageValidate operation results at the receiverLocate abnormalities and restore the next operationReferencesRelated guides

01Where path scheduling occurs in the instrument

Build a state table for reagents, stations and waste destinations. Include shared-pump or shared-valve occupancy, queuing, displacement and interlocks in scheduling to prevent concurrent tasks competing for the path.

Port count alone does not establish whether one pump or valve can serve simultaneous tasks. Define occupancy, release and displacement conditions for each action to prevent conflicting resource use.

02Product responsibilities in this operation

Valves control the current source or destination; the associated drive performs metering or transfer. Port connections, actual positioning and shared-segment renewal must match the operation.

For sample preparation path scheduling, confirm all ports, valve states, pressures in each state, shared volume and exchange volume.

03Organize the sequence by actual architecture

  1. Create a port-state table for reagent sources, shared metering paths, processing stations and waste. Identify pumps, valves or channels that cannot serve two tasks simultaneously.
  2. After the current task acquires the required resources, check source, receiving station and allowable pressure, then switch paths and verify actual connections.
  3. Handle shared-section residue according to the next reagent or product requirements, sending displacement liquid to its designated destination. Perform the liquid operation after confirming arrival of the intended liquid.
  4. Record actual receipt and affected samples, then release resources after restoring the prescribed standby state. After interruption, retain occupancy and completed-volume records so another task cannot use an unrestored path.

04Define operating conditions for this task

Conditions, results and abnormality records for this operation
To defineDetails
Actual operating conditionsAll ports, valve states, pressures in each state, shared volume and flushing volume
Acceptance targetCheck unintended connections, leakage, backflow and post-switching residue in each state; measure flushing volume and arrival delay through the complete path
Fault localizationMisalignment, shared-segment residue or abnormal switching pressure may affect the next task

05Compare product configurations by the roles on this page

Configuration options for the product roles on this page
ProductConfiguration optionConditions to verify
MRV3 multiport rotary valveMultiple-source selectionCompare 10-, 16- and 24-port options and port diagrams; verify high-pressure suitability separately
  • MRV3 multiport rotary valve

06Validate operation results at the receiver

Check unintended connections, leakage, backflow and post-switching residue in each state; measure flushing volume and arrival delay through the complete path.

Validate working volume, timing across workstations, sample identity and the first operation after restart together.

07Locate abnormalities and restore the next operation

Misalignment, shared-segment residue or abnormal switching pressure may affect the next task.

Stop the pump, check port states and flush again after recovery.

Successful platform operation does not replace assessment of nucleic acid, cell or analytical method results.

References

View references (1)
  1. [1]FOREACH MRV3 multiport rotary valve: configurations and specifications

Related guides

  • Return to the sample preparation workstation overview
  • Multiport rotary valves in sample preparation platforms

Related Products

MRV3 multiport rotary valve; representative configuration. Select capacity, materials and interfaces for the application.

MRV3 multiport rotary valve

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Discuss fluidic configurations for your sample preparation workstation

Provide a fluid diagram, the actual liquids and pressures in each state. Compare 10-, 16- and 24-port configurations against the port map, and assess high-pressure suitability separately. Compare suitable configurations against the validation objectives described here.

Contact an engineer