What do these products do in this instrument?
Syringe pumps: standards, dilution and internal-standard preparation
Deliver stock, diluent or internal standard separately in liquid sample-preparation branches, coordinated with source selection and mixing vessels. Confirm preparation volumes separately from continuous-flow requirements at the instrument introduction interface.
HLD and HMD organize aspiration/dispensing paths with rotary and solenoid valves respectively. Capacity budgets include useful volume, holding stages and replenishment points; valve states and pump actions together create each delivery.
Organize syringe metering around aspiration, holding and dispensing
Syringe drives use controlled displacement for aspiration, holding and dispensing. With direct contact, source liquid enters the metering chamber; with system-liquid drive, sample can remain at the probe tip or a designated tube segment. Define wetted coverage before capacity, cleaning and replenishment. For repeated dispensing, track current inventory, delivered volume and next replenishment time.
Map valve connections to every action
Check port connections, opening/closing sequence and power-off state separately for rotary- and solenoid-valve configurations. Changing source does not automatically remove old liquid from the chamber or shared tubing. Plan flushing for formulation and residue requirements, then evaluate the first dose after switching and dose-to-dose variation.
Translate actual branch conditions into configuration requirements
| Condition | To confirm |
|---|---|
| Stored volume and timing | Define volume per operation, consecutive dispensing count, holding time and permitted replenishment window. |
| Valve positions and destinations | Provide a source, receiver and waste port diagram with open/closed and power-off states. |
| Liquid changes and first dose | Check shared residue, priming destination and actual received volume after standby or source changes. |
| Operation | Specific operating conditions |
|---|---|
| Discrete liquid-sample transfer and introduction conditions | Actual sample volume, remaining source volume, probe-tip height, aspiration/dispensing speed and system liquid |
| Standards and dilution | Actual volumes of original sample, diluent or internal standard; concentrations at each stage; mixing and resampling conditions |
Compare product configurations by the roles on this page
| Product | Configuration option | Conditions to verify |
|---|---|---|
| HLD rotary-valve syringe pump | Aspiration, holding and dispensing with a rotary valve | Check source/outlet valve positions, capacity budget and replenishment timing |
| HMD solenoid-valve syringe pump | Metered aspiration and dispensing with solenoid valves | Check open/closed and power-off states, working volume and replenishment cycle |
Explore specific operating and validation tasks
Discrete liquid-sample transfer and introduction conditions
Delivery to a dilution vessel primarily requires volume control; delivery to an introduction interface also requires system-specific continuous flow, pulsation and pressure checks. Evaluate materials and sample-change recovery using the actual matrix.
Standards and dilution
Measure delivery of stock, diluent and internal standard separately, then validate the resulting concentration or method response after mixing. Shared-section residue can produce an incorrect composition despite correct commanded volumes.
Confirm product roles in actual operation
| Operation | Measurements and observations | Priority checks |
|---|---|---|
| Discrete liquid-sample transfer and introduction conditions | Measure actual delivery at the receiver, covering routine small volumes and maximum task volume, first dose after idle, sample changes and high/low concentration sequences | Air aspiration, clots/particles, probe contact with a wall or leakage alter actual delivery |
| Standards and dilution | Measure each branch's delivery, received ratio and mixing uniformity separately, then check assay response | Small-volume errors, shared residual liquid or inadequate mixing may alter the actual ratio |
Check concentration ratios, mixing, blank recovery and method results. Evaluate preparation and sample supply separately.
For repeated dispensing from one chamber, is checking total volume enough?
Measure each received dose, especially the first and last. Even when total volume is near target, individual errors may differ. Relate replenishment, valve switching and receiving actions to each result.
A sample-preparation pump is not automatically suitable for nebulizer supply. Confirm the introduction system for the specific instrument.