What do these products do in this instrument?
Filters: Method-Required Sample Treatment
Retain or remove particles where the analytical objective permits, according to the cells, biomass or dissolved analytes being measured. Check composition before and after filtration, adsorption, pressure drop and recovery after maintenance separately.
Filters provide method-permitted particle retention or component protection. Target components, pore size and filter material guide selection. Assess pressure drop, adsorption and recovery after replacement in the actual path.
Tubing and fittings: connecting process ports, pretreatment and analysis
Form the actual path to the receiving or analytical position. Set refresh conditions from materials, hold-up volume and delay. Include all connections in analyte-recovery, contamination and maintenance-recovery checks.
Tubing and fittings together form sealed connections and the actual transfer path. Check formulation, inner/outer diameters, length, tube-end positioning and port geometry, including added volume in residue and arrival delay.
Design tubing and fittings as a complete wetted path
Tubing, fittings and ports jointly determine sealing, transfer volume and medium-contact coverage. Materials and dimensions must suit formulation, operating conditions and installation. Include tubing length and interface volume in priming, shared residue and arrival delay. After connection changes, recheck delivery and cleaning through the actual path.
Check analyte retention while protecting components
Filters provide method-permitted particle retention or component protection. With actual samples and filter materials, check adsorption, blanks, pressure drop and flow changes as loading accumulates, while measuring analyte recovery. The specific method must validate whether the filtrate remains suitable for analysis.
Translate actual branch conditions into configuration requirements
| Condition | To confirm |
|---|---|
| Materials and assembly | Provide formulation, tubing inner/outer diameters, length, fitting structure and port fit. |
| Volume and load | Calculate shared and replacement-component added volumes; measure actual flow and response. |
| Filtration and method requirements | Confirm filter material and pore size. Compare analyte recovery, blanks and pressure drop before and after fouling, and record recovery after replacement. |
| Operation | Specific operating conditions |
|---|---|
| Filtration | Analytical target, filter material/pore size, filtration location, added volume, actual pressure drop and permitted maintenance |
Compare product configurations by the roles on this page
| Product | Configuration option | Conditions to verify |
|---|---|---|
| PE-Series Filters | Particle retention permitted by the method | Cards show representative configurations. Select actual pore size and filter material for the target, pressure drop and recovery requirements. |
| Tubing materials and dimensions | Connection paths and shared volume | Bore, length, load and actual formulation jointly determine materials and dimensions |
| Rigid-tubing fittings | Tube-end positioning and sealed connections | Check tube outer diameter, threads, seal structure and port-bottom geometry |
Explore specific operating and validation tasks
Filtration
Filter adsorption, increasing pressure drop and replacement can change a sample. Record method-specified particle treatment and before/after filtration differences.
Confirm product roles in actual operation
| Operation | Measurements and observations | Priority checks |
|---|---|---|
| Filtration | Compare analytes, recovery and blanks before and after filtration. Check pressure drop and actual flow after loading accumulates, and the first sample after replacement. | Blockage, adsorption, leakage or added filter-assembly volume can change the sample and its arrival time. |
Compare process and collected samples, checking target retention, contamination and reactor-volume changes.
Does a fitting that tightens prove the tubing assembly is suitable?
Also confirm port geometry, tube-end positioning and seal fit. Check leakage, hold-up and performance after repeated maintenance under actual conditions; thread engagement alone is insufficient.
Removing cell aggregates may change the measured target. Reduced valve-body contact through a pinch valve does not make the entire path sterile.