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Home/Applications/In Vitro Diagnostics/Coagulation analyzer
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Diaphragm pumps in coagulation analyzers

Application guide

Focusing on cleaning-fluid supply for reusable paths in coagulation analyzers, this page explains diaphragm-pump location, coordination and configuration conditions, linking to related operating and validation tasks.

Applicable architecture

Coagulation instruments may run clotting, chromogenic or immunoturbidimetric methods. This page discusses coordination of liquid delivery and reaction timing. Define initiation, preincubation and reading rules by method rather than reducing every assay to the same clotting endpoint.[4]

Application guide

Coagulation analyzer

Coagulation analyzer
Diaphragm pumps in coagulation analyzers
Cleaning reused paths and recovering the first dose
Bubble and pressure sensing in coagulation analyzers
Tubing and fittings in coagulation analyzers
Multiport rotary valves in coagulation analyzers
Switching reagent sources and reaction paths
Piston pumps in coagulation analyzers
Assay-specified sample delivery
Sampling probes in coagulation analyzers
Syringe pumps in coagulation analyzers
Reagent arrival and reaction timing

On this page

What do these products do in this instrument?Assign liquid supply to a defined usage branchCoordinate supply windows with downstream receiving conditionsTranslate actual branch conditions into configuration requirementsCompare product configurations by the roles on this pageExplore specific operating and validation tasksConfirm product roles in actual operationDo similar nominal supply- and waste-pump flow rates make a matched pair?ReferencesRelated guides

01What do these products do in this instrument?

Liquid diaphragm pumps: cleaning-fluid supply for reusable paths

Supply wash fluid to probe-washing or other reusable wetted components in the actual configuration. Coordinate cleaning interfaces and drain destinations, checking residue effects in the first dose of the next reaction.

Compare DPL30, DPL60 and DPL30H by actual supply load. Wash-head, valve, tubing and container resistance jointly determine installed flow; check the supply window and receiving position together.

02Assign liquid supply to a defined usage branch

This page compares liquid diaphragm-pump configurations for suitable supply paths. Define source, point of use, working liquid and cycle time, then measure liquid arriving at the use point under actual load. Cleaning effectiveness also depends on formulation, coverage and contact time.

Further technical reading

  • What Are Cleaning, Wash and Rinse Pumps in IVD Systems, and Why Are Miniature Diaphragm Pumps Used?
  • How to Read a Diaphragm Pump Flow-Pressure Curve—and Predict Installed Flow
  • IVD Waste Aspiration: Liquid Pump or Vacuum Pump? Direct vs Indirect Aspiration

03Coordinate supply windows with downstream receiving conditions

Tubing, valves and end-use resistance change installed flow. Match supply to permitted container levels or cleaning inflow. Downstream drainage uses its own extraction architecture; check its media and container protection separately rather than inferring them from supply-pump capacity.

04Translate actual branch conditions into configuration requirements

Diaphragm-pump configuration conditions in coagulation analyzers
ConditionTo confirm
Inlet mediumDistinguish liquid-only flow, intermittent gas entrainment and foam, and confirm the aspiration modes permitted by the configuration.
Tubing and containersProvide suction lift, outlet load, tubing and waste-container conditions.
Actual supply and removalMeasure incoming liquid, residue and emptying at the station; check handling after full level, shortage or blockage.
Operations supported in this instrument
OperationSpecific operating conditions
Cleaning reused paths and recovering the first doseWash-fluid formulation, volume/time, spray/aspiration geometry, air/foam and waste capacity

05Compare product configurations by the roles on this page

Configuration options for the product roles on this page
ProductConfiguration optionConditions to verify
DPL30 liquid diaphragm pumpLiquid supply or auxiliary circulationSelect by installed resistance, actual wash or working fluid and task window
DPL60 liquid diaphragm pumpLiquid supply or auxiliary circulationJudge by peak demand and installed operating point, not free flow alone
DPL30H high-backpressure liquid diaphragm pumpLiquid branches requiring higher backpressure capabilityCalculate pressure budget and actual flow first, then confirm interfaces and materials
  • DPL30 liquid diaphragm pump

    DPL30 liquid diaphragm pump

    View Details
  • DPL60 liquid diaphragm pump

    DPL60 liquid diaphragm pump

    View Details
  • DPL30H high-backpressure liquid diaphragm pump

    DPL30H high-backpressure liquid diaphragm pump

    View Details

06Explore specific operating and validation tasks

Cleaning reused paths and recovering the first dose

Residual wash fluid may alter the next formulation or carry contamination. Check internal flushing, external coverage and the first dose through the cleaned path, evaluating residue effects with the assay.

  • Cleaning reused paths and recovering the first dose

07Confirm product roles in actual operation

Operating-point validation and fault localization
OperationMeasurements and observationsPriority checks
Cleaning reused paths and recovering the first doseConfirm supply and peak waste-removal capacity under installed resistance; measure residual liquid, carryover or assay-specified recoveryInsufficient supply, foam, dry aspiration and a full waste container disrupt the cleaning cycle

Measure actual delivery and trigger timing at the reaction site and assess the effect of post-wash residue on the assay.

08Do similar nominal supply- and waste-pump flow rates make a matched pair?

Compare peak inflow, effective aspiration and permissible accumulation in the actual installation. The branches may handle different media and operating windows; validate station recovery over the complete sequence.

Pump or valve response time is not the reagent-contact or instrument measurement-start time.

References

View references (4)
  1. [1]FOREACH DPL30 liquid diaphragm pump: configurations and specifications
  2. [2]FOREACH DPL60 liquid diaphragm pump: configurations and specifications
  3. [3]FOREACH DPL30H high-backpressure liquid diaphragm pump: configurations and specifications
  4. [4]Sysmex CA-600: clotting, chromogenic and immunoturbidimetric configurations

Related guides

  • Back to the coagulation analyzer fluidics overview
  • Cleaning reused paths and recovering the first dose

Related Products

DPL30 Liquid diaphragm pumps

DPL30 Liquid diaphragm pumps

DPL60 Liquid diaphragm pumps

DPL60 Liquid diaphragm pumps

DPL30H High-backpressure liquid diaphragm pumps

DPL30H High-backpressure liquid diaphragm pumps

Related Technical Articles

What Are Cleaning, Wash and Rinse Pumps in IVD Systems, and Why Are Miniature Diaphragm Pumps Used?

Cleaning pump, wash pump and rinse pump usually name different duties within an IVD cleaning sequence, not three fixed pump mechanisms. Selection starts with wash volume, cycle rate, line resistance, wetted materials, and whether the duty is liquid supply or waste aspiration.

2026-09-03View Details

How to Read a Diaphragm Pump Flow-Pressure Curve—and Predict Installed Flow

A catalogue value such as 300 or 600 mL/min is not a fixed flow rate inside an instrument. The useful engineering question is: at the actual inlet pressure, outlet backpressure, fluid, tubing and supply voltage, where will the pump and the fluidic circuit settle?

2026-07-28View Details

IVD Waste Aspiration: Liquid Pump or Vacuum Pump? Direct vs Indirect Aspiration

Probe washing, reaction-cup cleaning, and routine waste removal in IVD instruments are all described as “waste aspiration.” Yet whether waste passes directly through a liquid pump or first enters a collection bottle while a vacuum pump creates negative pressure leads to entirely different selection logic.

2026-08-09View Details

Discuss Your IVD Fluidic Requirements

Share the instrument type, sample and reagent properties, working volumes, cycle timing, fluid path and acceptance criteria so we can discuss suitable components and prototype evaluation.

Discuss your application