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Home/Applications/In Vitro Diagnostics/Hematology analyzer
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Multiport rotary valves in hematology analyzers

Application guide

Hematology valve selection connects sample preparation to the detection channel required by the method. Define the actual reagent and channel states before choosing ports, and include the renewal and cleaning sequence that allows the next sample to enter a recovered channel.

Applicable architecture

Hematology analyzers may use different detection principles and channel configurations. Diluent, lysing reagent and sheath-fluid locations depend on the specific method; sheath-flow conditions do not apply to every counting channel.[2]

Application guide

Hematology analyzer

Hematology analyzer
Diaphragm pumps in hematology analyzers
Hematology-channel cleaning and waste removal
Bubble and pressure sensing in hematology analyzers
Tubing and fittings in hematology analyzers
Multiport rotary valves in hematology analyzers
Detection-channel switching and fluid renewal
Piston pumps in hematology analyzers
Whole-blood sampling and delivery
Sampling probes in hematology analyzers
Syringe pumps in hematology analyzers
Diluent and reaction-reagent metering

On this page

What do these products do in this instrument?Build the connection map from the detection architecturePlan renewal between preparation, measurement and cleaningTranslate actual branch conditions into configuration requirementsCompare product configurations by the roles on this pageExplore specific operating and validation tasksConfirm product roles in actual operationCan one valve-state program serve every hematology detection channel?ReferencesRelated guides

01What do these products do in this instrument?

Multiport rotary valves: sample processing and channel-path selection

Route the required reagent, prepared sample or wash source to its intended branch where selection is needed. Bind each valve state to the corresponding preparation or detection stage so the receiving channel and the liquid in the shared segment remain known.

MRV3 selects sources or destinations and requires a port-state diagram and shared-volume budget. Port count indicates routing options; confirm pressure in each state and independent simultaneous supply requirements separately.

02Build the connection map from the detection architecture

Identify which paths perform metered dilution, reagent treatment and detection supply. Include sheath flow only where the chosen channel requires it. The valve arrangement must accommodate the relevant pressures and permitted overlap of operations; a single selector cannot be assumed to provide independent simultaneous supply merely because it has enough source ports.

Further technical reading

  • Rotary Valve Selection Guide: From Fluid Paths to System Validation
  • Choosing Rotary Valve Wetted Materials: Head, Rotor and Seals

03Plan renewal between preparation, measurement and cleaning

Switching from a prepared sample to wash liquid, or from washing back to the next sample, changes what remains in the common segment. Define the discharge route and method-required renewal before detection resumes. If shared routing cannot meet channel preparation and timing requirements, reconsider which branches share the valve rather than increasing a nominal source flow.

04Translate actual branch conditions into configuration requirements

Multiport rotary-valve configuration conditions in hematology analyzers
ConditionTo confirm
Channel architectureList actual preparation and detection branches, media and required operating states; identify metered tasks separately from continuous supply.
Pressure and concurrencyProvide pressure in each source/receiver state and the operations that must overlap, including isolation from an inactive channel.
Renewal and cleaningMap sample, wash and discard destinations, with the channel blank and recovery evidence required before the next measurement.
Operations supported in this instrument
OperationSpecific operating conditions
Detection-channel switching and fluid renewalMethod-specific preparation/detection connections, state pressures, channel overlap, shared-liquid renewal and the blank required after washing or interruption

05Compare product configurations by the roles on this page

Configuration options for the product roles on this page
ProductConfiguration optionConditions to verify
MRV3 multiport rotary valveMultiple-source selectionCompare 10-, 16- and 24-port options and port diagrams; verify high-pressure suitability separately
  • MRV3 multiport rotary valve

    MRV3 multiport rotary valve

    View Details

06Explore specific operating and validation tasks

Detection-channel switching and fluid renewal

Confirm detection-channel flow and pressure by assay. Check channel renewal, blank recovery and bubbles separately; auxiliary source rated flow does not directly represent the detection branch.

  • Detection-channel switching and fluid renewal

07Confirm product roles in actual operation

Operating-point validation and fault localization
OperationMeasurements and observationsPriority checks
Detection-channel switching and fluid renewalRun the actual preparation-to-detection and cleaning-to-sample transitions. Measure channel conditions, liquid renewal and blanks, then assess the method response after switching.A correctly selected port may still deliver an old preparation or an air segment from the shared path. Inspect renewal and inactive-channel leakage before assigning the change to sample counting.

Validate the selected path with the channel actually receiving liquid. Retain separate evidence for metered preparation, any required detection supply and the first measurement after channel recovery.

08Can one valve-state program serve every hematology detection channel?

Only if it matches their actual media, pressure and renewal requirements. Different channel architectures can require different preparation and supply states; verify each intended path instead of copying a sheath-flow sequence to all channels.

Metered dilution and sheath-fluid flow are different roles; sheath-fluid requirements depend on the detection architecture.

References

View references (2)
  1. [1]FOREACH MRV3 multiport rotary valve: configurations and specifications
  2. [2]Sysmex hematology analyzer reference: impedance and fluorescence flow-cytometry configurations

Related guides

  • Back to the hematology analyzer fluidics overview
  • Detection-channel switching and fluid renewal

Related Products

MRV3 Rotary valves

MRV3 Rotary valves

Related Technical Articles

Rotary Valve Selection Guide: From Fluid Paths to System Validation

Map the connections required at each step before comparing specifications. Use the actual liquids, tubing and switching sequence to validate suitability for your instrument.

2026-09-30View Details

Choosing Rotary Valve Wetted Materials: Head, Rotor and Seals

Identify every component in contact with liquid before comparing PEEK, PCTFE and other candidates. Evaluate chemical compatibility, dynamic sealing and analytical results together.

2026-09-30View Details

Discuss Your IVD Fluidic Requirements

Share the instrument type, sample and reagent properties, working volumes, cycle timing, fluid path and acceptance criteria so we can discuss suitable components and prototype evaluation.

Discuss your application