Foreach TechnologyForeach Technology
Home
Products
Applications
About Us
Contact & Partnership
简体中文EnglishEspañolFrançais한국어Русский
Home
Products
Pump SeriesValve SeriesTubing SeriesFitting SeriesProbe SeriesSmart Control SeriesTubing Assemblies
Applications
All applicationsIVD DiagnosticsLife SciencesLaboratory AutomationAnalytical InstrumentsEnvironmental MonitoringSynthetic Biology
Resources
DatasheetsFluid Resistance CalculatorFitting ReplacementInstallation GuidesMaterial CompatibilityTechnical ArticlesCompany News
About Us
About ForeachR&D and ManufacturingQuality System and QualificationsMilestonesForeach Culture
Contact & Partnership
Contact UsBecome a Distributor
  • Pump Series
  • Valve Series
  • Probe Series
  • Fitting Series
  • Tubing Series
  • Control Series
  • Tubing Assemblies
  • All applications
  • IVD
  • Life Science
  • Lab Automation
  • Analytical Instruments
  • Environmental Monitoring
  • Synthetic Biology
  • Datasheets
  • Fluid Resistance Calculator
  • Fitting Replacement
  • Installation Guides
  • Material Compatibility
  • Technical Articles
  • Company News
  • About Foreach
  • R&D & Manufacturing
  • Quality & Compliance
  • History
  • Foreach Culture
  • Inquiry Form
  • Contact Information

Shenzhen Foreach Technology Co., Ltd.

Address: 13th Floor, 2nd Building, Yufengda Industrial Park, 1008th Guang Qiao Boulevard, Guangming District, Shenzhen 518132 CHINAView Map

Email: [email protected]

Tel: +86 755 8655 3831

LinkedInYouTubeFacebookInstagramX

© 2026 Shenzhen Foreach Technology Co., Ltd. All rights reserved.

Privacy Policy·

Home/Applications/In Vitro Diagnostics/Immunoassay analyzer
< Back

Sampling and wash probes in immunoassay analyzers

Application guide

Focusing on sample/reagent container interfaces, wash addition and aspiration with solid-phase retention in immunoassay analyzers, this page explains sampling- and wash-probe locations, coordination and configuration conditions, linking to related operating and validation tasks.

Applicable architecture

This page focuses on immunoassays with solid-phase separation washing, using magnetic particles as the bead-washing example. Confirm whether the specific assay requires separation washing and what solid phase it uses. Other architectures require branches defined by the actual instrument workflow. Candidate pumps and valves do not represent complete-instrument analytical performance.[3]

Application guide

Immunoassay analyzer

Immunoassay analyzer
Diaphragm pumps in immunoassay analyzers
Fluid supply and waste removal for magnetic solid-phase washing
Bubble and pressure sensing in immunoassay analyzers
Tubing and fittings in immunoassay analyzers
Fluidic valves in immunoassay analyzers
Isolation of reagent and wash-fluid paths
Piston pumps in immunoassay analyzers
Sample addition with a fixed probe
Sampling and wash probes in immunoassay analyzers
Syringe pumps in immunoassay analyzers
Multiple-reagent aspiration and dispensing

On this page

What do these products do in this instrument?Match component geometry to actual containersEvaluate interfaces by receiving or cleaning resultsTranslate actual branch conditions into configuration requirementsCompare product configurations by the roles on this pageRelated operations and architecture comparisonsConfirm product roles in actual operationCan sampling and wash probes be replaced based on similar appearance alone?ReferencesRelated guides

01What do these products do in this instrument?

Sampling probes: sample or reagent container interfaces

Aspirate and deliver to reaction vessels in probe-based architectures, coordinated with metering drive and probe washing. Evaluate tip geometry, droplets and cleaning after source changes together.

Custom sampling probes connect source containers to receiving positions. Diameter, tip, surface and interface depend on sample and container. Tip geometry must work with metering drive and motion sequences.

Wash probes: wash addition and aspiration while retaining solid phase

Form supply or aspiration interfaces at separation-washing stations. In magnetic-bead architectures, define height with magnetic capture and container geometry, balancing residual-liquid removal against solid-phase retention.

Custom wash probes form the container interface for wash-fluid entry or residual-liquid extraction. Confirm supply coverage, aspiration height and drainage timing together with actual container shape.

02Match component geometry to actual containers

Sampling and wash probes must fit container openings, bottoms, minimum levels and motion strokes. Record actual contact surfaces and permitted positions before defining tips, interfaces and motion space; appearance alone is insufficient for selection.

Further technical reading

  • Piston Pump Accuracy, Repeatability and Resolution Explained
  • What Are Cleaning, Wash and Rinse Pumps in IVD Systems, and Why Are Miniature Diaphragm Pumps Used?
  • Why do multiple wash nozzles deliver different flows from one miniature diaphragm pump?

03Evaluate interfaces by receiving or cleaning results

At the source, check reachable positions and low remaining volume; at the receiver, check actual volume, droplets or permitted residue. Test wetted-surface maintenance and recovery for the next container during consecutive operation. Reconfirm position and delivery after changing probes, tubing length or containers.

04Translate actual branch conditions into configuration requirements

Sampling- and wash-probe configuration conditions in immunoassay analyzers
ConditionTo confirm
Container and positionProvide opening, bottom, minimum level, positioning error and available motion space.
Liquid contact and surfacesSpecify sample or reagent, residue requirements and internal/external probe cleaning.
Actual functionCheck delivery, coverage, residue, solid-phase retention or mixing results according to the task.
Operations supported in this instrument
OperationSpecific operating conditions
Sample addition with a fixed probeActual sample volume, remaining source volume, probe-tip height, aspiration/dispensing speed and system liquid
Multiple-reagent aspiration and dispensingDose per operation, total cycle volume, replenishment/bottle-change interval, backpressure and receiving geometry
Fluid supply and waste removal for magnetic solid-phase washingSolid-phase location and retention target, wash cycles, aspiration height, residue, destination and downstream assay requirements

05Compare product configurations by the roles on this page

Configuration options for the product roles on this page
ProductConfiguration optionConditions to verify
Custom sampling probeSampling interface between source container and fluidic pathCompare custom geometry by minimum liquid level, probe-tip clearance and actual sample
Custom wash probeWashing interface for probe interiors/exteriors or containersConfirm contaminated surfaces, coverage, aspiration height and peak waste removal
  • Custom sampling probe

    Custom sampling probe

    View Details
  • Custom wash probe

    Custom wash probe

    View Details

06Related operations and architecture comparisons

Sample addition with a fixed probe

Sample-volume error affects reaction ratios, while external probe droplets may contaminate the next container. Combine aspiration, delivery and probe washing into a complete sequence and compare recovery after concentrated samples.

  • Sample addition with a fixed probe

Multiple-reagent aspiration and dispensing

Bead suspensions, binding reagents and substrates may have different settling, light and storage requirements. Plan standby, mixing and first-dose recovery by actual formulation, including residual liquid in shared tubing.

  • Multiple-reagent aspiration and dispensing

Fluid supply and waste removal for magnetic solid-phase washing

Record added volume, residual liquid and bead loss in every wash. If background is abnormal, distinguish inadequate capture, coverage, aspiration positioning and waste pooling before changing pump output.

  • Fluid supply and waste removal for magnetic solid-phase washing

07Confirm product roles in actual operation

Operating-point validation and fault localization
OperationMeasurements and observationsPriority checks
Sample addition with a fixed probeMeasure actual delivery at the receiver, covering routine small volumes and maximum task volume, first dose after idle, sample changes and high/low concentration sequencesAir aspiration, clots/particles, probe contact with a wall or leakage alter actual delivery
Multiple-reagent aspiration and dispensingUse actual media to check first, middle and last doses and delivery after bottle changes; confirm received volume and timing rather than substituting commanded steps for volumeEmpty sources, bubbles, nozzle droplets and backpressure changes affect first or last doses
Fluid supply and waste removal for magnetic solid-phase washingMeasure bead loss, post-wash residue and downstream assay background for each wash; do not evaluate washing by volume or recovery aloneInsufficient magnetic capture, misplaced aspiration, wash coverage or waste pooling may increase background

Evaluate reagent delivery, post-wash residue, bead loss and assay background together.

08Can sampling and wash probes be replaced based on similar appearance alone?

Confirm tip, channels, interfaces and operating positions separately, then validate each probe's aspiration/dispensing or cleaning results. Similar appearance does not imply equal wetted volume, coverage or residual-liquid levels.

Pump flow alone does not prove adequate washing; validate magnetic capture, mixing and aspiration position across the whole station.

References

View references (3)
  1. [1]FOREACH custom sampling probes: configurations and specifications
  2. [2]FOREACH custom wash probes: configurations and specifications
  3. [3]Beckman Coulter Access: an assay example of magnetic solid-phase separation, washing and substrate detection

Related guides

  • Back to the immunoassay analyzer fluidics overview

Related Products

Sampling probes

Sampling probes

Wash probes

Wash probes

Related Technical Articles

Piston Pump Accuracy, Repeatability and Resolution Explained

Learn why theoretical volume per step is not the minimum reliable dose, and how accuracy, repeatability, valves, bubbles and working stroke affect dispensing results.

2026-09-06View Details

What Are Cleaning, Wash and Rinse Pumps in IVD Systems, and Why Are Miniature Diaphragm Pumps Used?

Cleaning pump, wash pump and rinse pump usually name different duties within an IVD cleaning sequence, not three fixed pump mechanisms. Selection starts with wash volume, cycle rate, line resistance, wetted materials, and whether the duty is liquid supply or waste aspiration.

2026-09-03View Details

Why do multiple wash nozzles deliver different flows from one miniature diaphragm pump?

Calculate demand from the volume and timing of each wash nozzle, separate insufficient pump output from unequal distribution, and verify each branch with collection and pressure measurements.

2026-09-08View Details

Discuss Your IVD Fluidic Requirements

Share the instrument type, sample and reagent properties, working volumes, cycle timing, fluid path and acceptance criteria so we can discuss suitable components and prototype evaluation.

Discuss your application