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Fluidic Monitoring: Using Bubble and Pressure Signals in Control

Application guide

Bubble and pressure monitoring identifies fluid-path conditions. These signals do not independently establish actual dose or analytical results. Control decisions require sensor location, action stage and time window to be considered together.

Application guides

Analytical instruments

Analytical instruments Overview
Liquid chromatography systems: locate the fluidic task before selecting pumps and valves
Spectroscopy and elemental analysis
Water analysis units
Analytical Sample Preparation
Analytical system integration
Piston Pumps in Analytical Instruments
Automated dilution with piston pumpsPiston Pump Titration
Syringe pump
Syringe-pump samplingMultiple dispensing with syringe pumpsSyringe-pump standard preparation and over-range sample dilutionSequential injection and flow analysis
Air-displacement pipetting pump
Disposable-Tip Sample TransferTip-based dilution and dispensingTip-based sample preparation
Valveless metering pumps
Repeated Dispensing with Valveless PumpsValveless-pump titrationCarrier-liquid and flow-cell supplyTwo-stream proportioning
Diaphragm pump
Wash-liquid supply and primingWorking-liquid replenishmentAuxiliary liquid circulationGas-liquid waste aspiration
Valves for Analytical Fluidics
MRV3 multi-source selectionHigh-pressure sample-loop injectionDetector Flow Diversion and BypassSolenoid-valve shutoff
Sampling, Washing and Mixing Components
Sampling needlesProbe-wash stationReaction-cup and microplate washingReaction mixing
Fluidic monitoring
Bubble and Liquid-State DetectionPressure and Blockage Monitoring
Tubing, fittings, filters and check valves
Tubing materials and dimensionsLow-retention connectionsFiltration and backflow protection

ON THIS PAGE

Locate the source, drive and receiving position for this taskSelect sensing position and range from the target faultsCompare product options against task requirementsEstablish decision criteria for each action stageTest detection, false alarms and recoveryAfter an abnormality or maintenance, first identify which segment needs recoveryContinue with tasks on the same branchReferencesRelated guides

01Locate the source, drive and receiving position for this task

Liquid path→Bubble or pressure measurement location→State assessment→Alarms and process recovery
Functional or operational sequence; confirm connections and branches for each state on the instrument

Required inputs are the specific sensor configuration, location, liquid/tubing, sampling rate, thresholds and time windows. Confirm liquid contact, pressure and destination along each illustrated section before defining drive and connection responsibilities.

02Select sensing position and range from the target faults

Define target faults and permitted response time before selecting sensing locations, tubing and signal range. Confirm ABD and PDM5 capabilities for the actual configuration; unverified ranges or accuracy are not guaranteed.

Compare configuration conditions by actual task
Condition to compareInformation requiredSelection affected
Monitoring objectiveLoss of liquid supply, bubbles, blockage or leakageSelect measurement locations and supporting checks
Time correlationCurrent aspiration, dosing or switching stageDefine appropriate signal ranges for different actions
Controller responsePotentially affected sample, recorded delivery and restart conditionsConnect alarms to actionable responses

03Compare product options against task requirements

The following candidate options match this page's responsibilities. Compare them against the operating conditions described, then check capacity, materials and interfaces on the product pages. Card images show representative configurations; suitability must still be confirmed at actual operating points and by application results.

Move from task conditions to product configuration
Product categoryCorresponding roleConfirm before selection
ABD bubble-detection moduleBubble or liquid-state identification in defined tubingValidate detection and false alarms for tubing material, dimensions, medium and action window
PDM5 pressure-detection modulePressure-state monitoring at a defined fluidic locationConfirm range and wetted configuration by model; validate normal baseline and abnormalities separately
  • ABD bubble-detection module
  • PDM5 pressure-detection module

04Establish decision criteria for each action stage

Establish normal-operation baselines and assess sampling, dosing, washing and shutdown separately. The controller should associate alarms with the current sample, valve position and recorded delivery before deciding whether to stop, retry or flag an operation.

Action records should link commands, valve or interface states and actual received results. When raw material, container or sample identity changes, reconfirm shared paths and conditions permitting the next step. Completion of drive movement alone does not replace task acceptance.

05Test detection, false alarms and recovery

Introduce controlled air aspiration, blockage, leakage and bubbles, and measure false alarms and recovery. Normal sensor output only describes the monitored state; it does not replace received-volume or method acceptance tests.

Link operating-point tests to interpretable results
Validation scenarioMeasurement or observationInterpretation and action
Fault detectionIntroduce controlled faults and record false alarmsEvaluate detection rate and false alarms together
Release after recoveryCompare signals with the actual liquid stateRecheck affected deliveries even after signals return to normal

Record test medium, configuration, installed path and operating sequence; present routine operating points and boundary results separately. Calculations support design discussions, component documentation checks models, and installed measurements confirm the actual task.

06After an abnormality or maintenance, first identify which segment needs recovery

Normal air segments, viscosity changes and sampling delays may be misclassified. The controller determines task validity; sensors alone do not prove dose or assay results.

Retain current source, container identity, completed actions, valve or interface state and actual receiving information. Use the table to locate the stage that changed before deciding to retry, continue or restart. After recovery, recheck the relevant operating point before returning an uncertain action to the automatic cycle.

  • Bring the fluidic diagram and operating-point records to discuss configuration

07Continue with tasks on the same branch

  • Bubble and Liquid-State Detection: Position, Speed and Debounce Time
  • Pressure and blockage monitoring: establish action baselines before fault thresholds

References

View references (2)
  1. [1]Sensirion: LD20 Liquid Flow Sensor and Fluid-Fault Detection
  2. [2]FOREACH: Fluid Monitoring and Control Product Range

Related guides

  • Bubble and Liquid-State Detection: Position, Speed and Debounce Time
  • Pressure and blockage monitoring: establish action baselines before fault thresholds

Related Products

ABD bubble-detection module; representative configuration. Select capacity, materials and interfaces for the application.

ABD bubble-detection module

PDM5 pressure-detection module; representative configuration. Select capacity, materials and interfaces for the application.

PDM5 pressure-detection module

Related Technical Articles

Why Do Air Bubbles Delay or Bias Piston Pump Dispensing?

A completed piston stroke does not prove that the intended liquid volume reached the vessel. Bubble compression temporarily stores displacement; expansion can then cause a trailing dispense or affect the next cycle. Locate where bubbles first appear and compare synchronized pressure and individual dispense masses before and after priming.

2026-09-10View Details

What is flow resistance calculation for? Using the Foreach calculator in fluid-path design and selection

The free flow rate of the pump meets the requirements. After installing the pipelines, valves and joints, the liquid supply at the end is insufficient. Flow resistance calculations can break the problem down into comparable data: what pressure differential is required at the target flow rate, where does the pressure loss mainly occur, and what happens if the pipe diameter, pipe length, component Cv or medium viscosity is changed. This article combines the actual function of the Foreach flow resistance calculator with a recalculable fluid circuit case to explain how to use the calculation results for design, selection, troubleshooting and prototype verification.

2026-09-11View Details

Discuss Your Fluidic Monitoring Configuration

Provide a fluid-path diagram, actual liquids and pressures in each state. Specify low-liquid, bubble, blockage or leak conditions, the current aspiration, dispensing or switching stage, affected samples, confirmed delivery and restart criteria. Compare configurations against the guide's validation objectives.

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