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Tubing, Fittings, Filters and Check Valves: Assess the Complete Flow Path

Application guide

Connections join pumps, valves and receivers into a complete path. Their volume, resistance, materials and maintenance arrangement affect delivery and response. Matching threads alone is insufficient for selection.

Application guides

Analytical instruments

Analytical instruments Overview
Liquid chromatography systems: locate the fluidic task before selecting pumps and valves
Spectroscopy and elemental analysis
Water analysis units
Analytical Sample Preparation
Analytical system integration
Piston Pumps in Analytical Instruments
Automated dilution with piston pumpsPiston Pump Titration
Syringe pump
Syringe-pump samplingMultiple dispensing with syringe pumpsSyringe-pump standard preparation and over-range sample dilutionSequential injection and flow analysis
Air-displacement pipetting pump
Disposable-Tip Sample TransferTip-based dilution and dispensingTip-based sample preparation
Valveless metering pumps
Repeated Dispensing with Valveless PumpsValveless-pump titrationCarrier-liquid and flow-cell supplyTwo-stream proportioning
Diaphragm pump
Wash-liquid supply and primingWorking-liquid replenishmentAuxiliary liquid circulationGas-liquid waste aspiration
Valves for Analytical Fluidics
MRV3 multi-source selectionHigh-pressure sample-loop injectionDetector Flow Diversion and BypassSolenoid-valve shutoff
Sampling, Washing and Mixing Components
Sampling needlesProbe-wash stationReaction-cup and microplate washingReaction mixing
Fluidic monitoring
Bubble and Liquid-State DetectionPressure and Blockage Monitoring
Tubing, fittings, filters and check valves
Tubing materials and dimensionsLow-retention connectionsFiltration and backflow protection

ON THIS PAGE

Locate the source, drive and receiving position for this taskCalculate complete-path volume and resistanceCompare product options against task requirementsPrime and inspect again after replacing connectionsAssess sealing, recovery and restart performance separatelyAfter an abnormality or maintenance, first identify which segment needs recoveryContinue with tasks on the same branchReferencesRelated guides

01Locate the source, drive and receiving position for this task

Pump or valve outlet→Tubing and connections→Filtration or backflow protection→Receiving and maintenance interfaces
Functional or operational sequence; confirm connections and branches for each state on the instrument

Define tubing ID/OD, length, interface geometry, pressure, materials and maintenance method. Follow the diagram to confirm liquid contact, pressure and destination before assigning drive and connection roles.

02Calculate complete-path volume and resistance

Record tubing ID, length, interface geometry, pressure, formulation and shared volume. Filters add volume and pressure drop; check valves add opening requirements. Include both in pump operating-point calculations.

Compare configuration conditions by actual task
Condition to compareInformation requiredSelection affected
Path geometryBore size, length, ports and shared volumeCalculate delay, retention and resistance
Wetted-contact requirementsActual liquid, temperature and cleaning conditionsConfirm materials component by component
Maintenance stateDisassembly, replacement and orientation requirementsDefine assembly records and recovery acceptance

03Compare product options against task requirements

The following candidate options match this page's responsibilities. Compare them against the operating conditions described, then check capacity, materials and interfaces on the product pages. Card images show representative configurations; suitability must still be confirmed at actual operating points and by application results.

Move from task conditions to product configuration
Product categoryCorresponding roleConfirm before selection
Tubing materials and dimensionsConnection paths and shared volumeBore, length, load and actual formulation jointly determine materials and dimensions
Rigid-tubing fittingsTube-end positioning and sealed connectionsCheck tube outer diameter, threads, seal structure and port-bottom geometry
PE-Series FiltersParticle retention permitted by the methodCards show representative configurations. Select actual pore size and filter material for the target, pressure drop and recovery requirements.
G-series check valvesBackflow limitationThe card shows a representative configuration. Confirm actual opening conditions, reverse leakage and medium separately.
  • Tubing materials and dimensions
  • Rigid-tubing fittings
  • PE-Series Filters
  • G-series check valves

04Prime and inspect again after replacing connections

Assemble to the drawing and verify flow direction. After priming, check leakage and actual flow. Reassess delay, residue and first-dose delivery after changing tube length, filters or fittings.

Action records should link commands, valve or interface states and actual received results. When raw material, container or sample identity changes, reconfirm shared paths and conditions permitting the next step. Completion of drive movement alone does not replace task acceptance.

05Assess sealing, recovery and restart performance separately

Validate sealing, installed resistance, analyte recovery and recovery after maintenance separately. Free passage does not prove that filtration preserves the sample or that dead volume meets method requirements.

Link operating-point tests to interpretable results
Validation scenarioMeasurement or observationInterpretation and action
Installed pathMeasure sealing, load and actual deliveryEvaluate operating performance even after a connection is successfully assembled
Method compatibilityCheck target recovery and blanksMechanical protection does not automatically establish that the analytical sample is unchanged

Record test medium, configuration, installed path and operating sequence; present routine operating points and boundary results separately. Calculations support design discussions, component documentation checks models, and installed measurements confirm the actual task.

06After an abnormality or maintenance, first identify which segment needs recovery

Misconnections, gaps, tube deformation or leaks may alter volume and pressure. Isolate the affected segment and reconfirm assembly; matching threads do not establish interchangeability.

Retain current source, container identity, completed actions, valve or interface state and actual receiving information. Use the table to locate the stage that changed before deciding to retry, continue or restart. After recovery, recheck the relevant operating point before returning an uncertain action to the automatic cycle.

  • Bring the fluidic diagram and operating-point records to discuss configuration

07Continue with tasks on the same branch

  • Tubing Materials and Dimensions: Volume, Resistance and Maintenance Layout
  • Low-Hold-Up Connections: Matching Threads, Tube Ends and Port Geometry
  • Filter and check-valve protection: analytes, resistance and maintenance limits

References

View references (2)
  1. [1]IDEX Health & Science: Fluidics FAQs — Dead Volume and Fittings
  2. [2]FOREACH: Fittings and Tubing Catalog

Related guides

  • Tubing Materials and Dimensions: Volume, Resistance and Maintenance Layout
  • Low-Hold-Up Connections: Matching Threads, Tube Ends and Port Geometry
  • Filter and check-valve protection: analytes, resistance and maintenance limits

Related Videos

Related Products

Tubing materials and dimensions; representative configuration. Select capacity, materials and interfaces for the application.

Tubing materials and dimensions

Rigid-tubing fittings; representative configuration. Select capacity, materials and interfaces for the application.

Rigid-tubing fittings

PE-Series Filters; representative configuration. Select capacity, materials and interfaces for the application.

PE-Series Filters

G-series check valves; representative configuration. Select capacity, materials and interfaces for the application.

G-series check valves

Related Technical Articles

What is flow resistance calculation for? Using the Foreach calculator in fluid-path design and selection

The free flow rate of the pump meets the requirements. After installing the pipelines, valves and joints, the liquid supply at the end is insufficient. Flow resistance calculations can break the problem down into comparable data: what pressure differential is required at the target flow rate, where does the pressure loss mainly occur, and what happens if the pipe diameter, pipe length, component Cv or medium viscosity is changed. This article combines the actual function of the Foreach flow resistance calculator with a recalculable fluid circuit case to explain how to use the calculation results for design, selection, troubleshooting and prototype verification.

2026-09-11View Details

Why Does Actual Flow Change So Much When the Tubing Size Changes on the Same Miniature Diaphragm Pump?

Even when the pump is unchanged, installed flow can change because of tubing inner diameter, length, bends, and the minimum bore of fittings. When flow falls after a tubing change, the effective response is neither to blame the pump first nor to enlarge every tube indiscriminately. Measure inlet pressure, outlet pressure, and accumulated flow together to determine where the added restriction actually occurs.

2026-08-24View Details

Miniature Diaphragm Pump Backflow After Stopping: Check Valves and Anti-Siphon Design

Diagnose reverse flow after a miniature diaphragm pump stops, distinguish it from forward siphoning and residual dripping, and evaluate check-valve behavior, valve sequencing and static sealing in the complete circuit.

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What Is a Quick Disconnect Fitting? Male/Female Connections, Valves and Selection

Select a quick disconnect for an instrument fluid path by checking the mating interface, shutoff requirements, tubing, seals and mounting space.

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Define the connection task first: joining two lines, branching or mounting through a panel. Then match every port and seal before selecting the bore, material and mounting arrangement.

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Select a PMB bulkhead hose barb and PMBSN nut by tubing ID, PP/PA material and panel conditions. Use dimensions, diameter ratios and fault symptoms to complete the selection.

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Discuss your tubing, fitting, filter and check-valve requirements

Provide a fluid diagram, the actual liquids and pressures in each state. Specify bore size, length, ports and shared volume; actual liquid, temperature and cleaning conditions; and disassembly, replacement and orientation requirements. Compare suitable configurations against the validation objectives described here.

Contact an engineer