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Analytical fluidic valves: source selection, injection, diversion and isolation

Application guide

Rotary, high-pressure and solenoid valves use different port connections for source selection, sample-loop injection, bypass and shutoff. Start selection with connections and pressures in every operating state, rather than names or port counts.

Application guides

Analytical instruments

Analytical instruments Overview
Liquid chromatography systems: locate the fluidic task before selecting pumps and valves
Spectroscopy and elemental analysis
Water analysis units
Analytical Sample Preparation
Analytical system integration
Piston Pumps in Analytical Instruments
Automated dilution with piston pumpsPiston Pump Titration
Syringe pump
Syringe-pump samplingMultiple dispensing with syringe pumpsSyringe-pump standard preparation and over-range sample dilutionSequential injection and flow analysis
Air-displacement pipetting pump
Disposable-Tip Sample TransferTip-based dilution and dispensingTip-based sample preparation
Valveless metering pumps
Repeated Dispensing with Valveless PumpsValveless-pump titrationCarrier-liquid and flow-cell supplyTwo-stream proportioning
Diaphragm pump
Wash-liquid supply and primingWorking-liquid replenishmentAuxiliary liquid circulationGas-liquid waste aspiration
Valves for Analytical Fluidics
MRV3 multi-source selectionHigh-pressure sample-loop injectionDetector Flow Diversion and BypassSolenoid-valve shutoff
Sampling, Washing and Mixing Components
Sampling needlesProbe-wash stationReaction-cup and microplate washingReaction mixing
Fluidic monitoring
Bubble and Liquid-State DetectionPressure and Blockage Monitoring
Tubing, fittings, filters and check valves
Tubing materials and dimensionsLow-retention connectionsFiltration and backflow protection

ON THIS PAGE

Locate the source, drive and receiving position for this taskDefine the port map and pressure states before selecting a modelCompare product options against task requirementsInterlock valve position, pump action and destinationValidate connectivity, leakage and flushing separatelyAfter an abnormality or maintenance, first identify which segment needs recoveryContinue with tasks on the same branchReferencesRelated guides

01Locate the source, drive and receiving position for this task

Liquid sources→Valve ports and states→Pump and shared flow path→Receiving or waste destination
Functional or operational sequence; confirm connections and branches for each state on the instrument

Define all ports, valve states, pressures in each state, shared volume and displacement volume. Follow the diagram to confirm liquid contact, pressure and destination before assigning drive and connection roles.

02Define the port map and pressure states before selecting a model

List ports, media, actual pressures, passage dimensions, shared volume and switching time. Compare the published 10-, 16- and 24-port MRV3 configurations for source selection. Confirm high-pressure injection and power-off isolation requirements separately.

Compare configuration conditions by actual task
Condition to compareInformation requiredSelection affected
Port connectivitySource and outlet for every valve positionDefine every switch with a state diagram
Pressure and mediumPressure and contact liquid in each stateSeparate low-pressure selection from high-pressure switching
Shared pathDead volume, displacement and switching timeInclude residue control in the cycle

03Compare product options against task requirements

The following candidate options match this page's responsibilities. Compare them against the operating conditions described, then check capacity, materials and interfaces on the product pages. Card images show representative configurations; suitability must still be confirmed at actual operating points and by application results.

Move from task conditions to product configuration
Product categoryCorresponding roleConfirm before selection
MRV3 multiport rotary valveMultiple-source selectionCompare 10-, 16- and 24-port options and port diagrams; verify high-pressure suitability separately
HP high-pressure injection valvePressurized injection-path switchingCheck port pressures and sample loops in loading, injection and other states
SV10 solenoid valveOn/off control or branch selectionCheck normal state, differential pressure, flow direction and duty cycle; high-pressure tasks require a separately suitable configuration
  • MRV3 multiport rotary valve
  • HP high-pressure injection valve
  • SV10 solenoid valve

04Interlock valve position, pump action and destination

Interlock valve position, pump actions and receiving direction. After positioning, determine whether the shared path needs flushing. Include maintenance and fault states in the diagram.

Action records should link commands, valve or interface states and actual received results. When raw material, container or sample identity changes, reconfirm shared paths and conditions permitting the next step. Completion of drive movement alone does not replace task acceptance.

05Validate connectivity, leakage and flushing separately

Check connectivity, leakage, displacement, pressure recovery and residue in each state. A multiport valve's port count does not establish independent parallel channels or high-pressure suitability.

Link operating-point tests to interpretable results
Validation scenarioMeasurement or observationInterpretation and action
Connectivity and sealingCheck flow direction and leakage in each stateA valve-position signal does not replace fluid-path validation
Source switchingAssess recovery with the most challenging liquid combinationsDetermine displacement conditions from residue results

Record test medium, configuration, installed path and operating sequence; present routine operating points and boundary results separately. Calculations support design discussions, component documentation checks models, and installed measurements confirm the actual task.

06After an abnormality or maintenance, first identify which segment needs recovery

Mispositioning, shared-path residue or abnormal switching pressure can affect the next task. Stop pumping and check ports, then flush again after restoring the correct state.

Retain current source, container identity, completed actions, valve or interface state and actual receiving information. Use the table to locate the stage that changed before deciding to retry, continue or restart. After recovery, recheck the relevant operating point before returning an uncertain action to the automatic cycle.

  • Bring the fluidic diagram and operating-point records to discuss configuration

07Continue with tasks on the same branch

  • MRV3 Multiple-Source Selection: Port Maps, Displacement and Challenging Liquid Combinations
  • High-Pressure Sample-Loop Injection: Loading and Injection States
  • Detector Diversion and Bypass: Delay Volume and Switching Disturbance
  • Solenoid Shutoff: Normal State, Energization Cycle and Fault Routing

References

View references (2)
  1. [1]VICI: Sample Injection with a Cheminert 6-Port Valve
  2. [2]FOREACH: Fluidic Valve Product Range

Related guides

  • MRV3 Multiple-Source Selection: Port Maps, Displacement and Challenging Liquid Combinations
  • High-Pressure Sample-Loop Injection: Loading and Injection States
  • Detector Diversion and Bypass: Delay Volume and Switching Disturbance
  • Solenoid Shutoff: Normal State, Energization Cycle and Fault Routing

Related Products

MRV3 multiport rotary valve; representative configuration. Select capacity, materials and interfaces for the application.

MRV3 multiport rotary valve

HP high-pressure injection valve; representative configuration. Select capacity, materials and interfaces for the application.

HP high-pressure injection valve

SV10 solenoid valve; representative configuration. Select capacity, materials and interfaces for the application.

SV10 solenoid valve

Related Technical Articles

Rotary Valve Selection Guide: From Fluid Paths to System Validation

Map the connections required at each step before comparing specifications. Use the actual liquids, tubing and switching sequence to validate suitability for your instrument.

2026-09-30View Details

How Does a 6-Port HPLC Injection Valve Work? Load, Inject and Vent

Follow sample loading into an external loop and transfer to the column by the mobile phase, distinguishing the HP valve's main positions and vent path from the factors that determine injection volume.

2026-09-29View Details

What Is a Solenoid Valve? Operating Principles and 2-Way/3-Way Fluid Control

Follow the fluid path after energization to understand how 2-way and 3-way solenoid valves handle reagent dispensing and washing, and how they work with pumps and control programs.

2026-09-29View Details

Discuss Your Analytical Valve Configuration

Provide a fluid diagram, the actual liquids and pressures in each state. Specify sources and outlets for every valve position; pressure and contact liquid in each state; and dead volume, displacement and actuation time. Compare suitable configurations against the validation objectives described here.

Contact an engineer